Jam with virtual instruments

I wonder if Pro Tools 11, that i use, are good for jamming with my electric guitar with virtual instruments with MIDI for example? I also use Energy XT, another DAW, and i wonder if somebody know the differens between these DAW in the context of jamming with virtual instruments, is Pro Tools better on that in some way? I should also say that i use AXON AX 100 MK ll as Guitar to MIDI controller/converter.